3 ms·

Since you seem well informed: does the research mention anything about use as an aerosol and why that might be considered before internal use?

• fabian2k 6y ago
  They wrote that regular antibodies have to be given intravenuously. These nanobodies are smaller and more stable, so they argue that it is possible to use them as aerosol. The idea seems to be to use them as prevention, which would not be feasible if you have to inject them. I can't really judge whether that approach makes sense, my experience is in the basic research area, not with clinical stuff.
  • Kwantuum 6y ago
    Right, but they do have the potential to also be used as treatment then? Considering they're easier to manufacture than synthetic antibodies.
  • mcintyre1994 6y ago
    Is the hypothesis of an aerosol as prevention that you could spray eg. an indoor area and prevent infected people who come into that area being able to infect others in an airborne way?
    • peeters 6y ago
      > In an aerosol formulation they tested, dubbed “AeroNabs” by the researchers, these molecules could be self-administered with a nasal spray or inhaler.