That's a great question. A lot of antibiotics are effluxed out so they don't build up to high levels within the cell. Also, a lot of antibiotics bind to part o

That's a great question. A lot of antibiotics are effluxed out so they don't build up to high levels within the cell. Also, a lot of antibiotics bind to part of the bacterial cell wall, which mitochondria lost over evolution. Antibiotics that inhibit protein synthesis actually do negatively impact mitochondrion but not as bad because of divergences in ribosomal structure compared to bacteria.