It's true that WebAssembly makes web apps more opaque, since it's a compiled binary vs JavaScript code. However, ad blocking should the same as for JavaScript

It's true that WebAssembly makes web apps more opaque, since it's a compiled binary vs JavaScript code. However, ad blocking should the same as for JavaScript single page apps. The Rust code in this article hooks into JavaScript APIs to create a standard webpage, using standard HTML elements and updating the DOM - just like a JS app would.