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If I understand correctly, the mRNA vaccines have the added benefit that there are no existing antibodies that destroy the modified virus, like the adenovirus v
by raducu 6y ago
If I understand correctly, the mRNA vaccines have the added benefit that there are no existing antibodies that destroy the modified virus, like the adenovirus vaccines.
Sure, the Oxford vaccine uses an adenovirus that is not present in humans outside Africa, but when they try to make a second vaccine, based on the same adenovirus, people who took the COVID-19 vaccine might not be protected.
So while not tested, mRNA might be a much better bet for the future, because we will be able to develop vaccines much faster and not have to search for a new virus vector each time a new vaccine is developed.
- mlyle 6y agomRNA would be a nice capability to have, if it doesn't kill people or cause excessive side effects. It looks like the side effects from mRNA vaccines are bigger than a typical vaccination. It's starting to look like mRNA vaccines may not be the vaccine you'd want in the long term based on this alone. The question is, do they create high severity side effects that preclude using them in the short term? We're about to learn... There's a lot of other efforts; adenovirus vectors, attenuated efforts, non-replicating virus efforts. Of course, the adenovirus vectors are of concern because if immunity wears off, you can't necessarily give someone a booster a couple years later.