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How do the randomly located specialist T-Cells that "clone into a battalion" after the messenger cell show up know where to go in the body? Do they just fan out
by op03 6y ago
How do the randomly located specialist T-Cells that "clone into a battalion" after the messenger cell show up know where to go in the body? Do they just fan out in all directions? Or is there some spl navigation mechanism?
Any good book reco's for the layman?
- anotherboffin 6y agoWell a lot of the T cells will enter the bloodstream in order to spread through the body. My knowledge of this is fairly limited but chemokines serve as the navigation instruments in many cases: a site of inflammation or infection will have immune cells expressing these signaling molecules that will slowly diffuse and create a gradient. T cells (for example) will follow this gradient to get to the site of interest (the process is called chemotaxis). No book recommendations off the top of my head, but I’ll post back if something comes up.
- yread 6y agoWe don't really have good explanations on "how does anything know where to go" in biology except "brownian motion" everything goes everywhere and if the association is strong enough it sticks