The original paper A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm [1]: > ...our results indicate that

The original paper A mechanistic model and therapeutic interventions for COVID-19 involving a RAS-mediated bradykinin storm [1]: > ...our results indicate that the pathology of COVID-19 is likely the result of Bradykinin Storms rather than cytokine storms (although given the induction of IL2 by BK, the two may be intricately linked). > Several interventional points (most of them already FDA-approved pharmaceuticals) could be explored with the goal of increasing ACE, decreasing BK, or blocking BK2 receptors (Table 1). [1] https://elifesciences.org/articles/59177 https://elifesciences.org/articles/59177