3 ms·
This seems curious. Methanol is toxic bit it's not novichok https://en.wikipedia.org/wiki/Methanol_toxicity https://en.wikipedia.org/wiki/Methanol_toxicity "Me
by throwaway_pdp09 6y ago
This seems curious. Methanol is toxic bit it's not novichok https://en.wikipedia.org/wiki/Methanol_toxicity https://en.wikipedia.org/wiki/Methanol_toxicity
"Methanol has a high toxicity in humans. As little as 10 mL of pure methanol when drunk is metabolized into formic acid, which can cause permanent blindness by destruction of the optic nerve. 15 mL is potentially fatal,[1] although the median lethal dose is typically 100 mL (3.4 fl oz) (i.e. 1–2 mL/kg body weight of pure methanol[8]). Reference dose for methanol is 0.5 mg/kg/day.[9]"
I've been using methylated spirits (~10% methanol IIRC, rest ethanol) as a hand sanitiser (on my hands, not as a flipping mouthwash) for months with no problems and I'm going to dig around and check its skin permeability tomorrow, but I wonder if the FDA is doing a bit of major just-in-case butt-covering here.
Edit: some links
https://chemistry.stackexchange.com/questions/24036/methanol-skin-exposure-serious-or-not https://chemistry.stackexchange.com/questions/24036/methanol...
Quite long.
https://link.springer.com/article/10.1007/BF00378331 https://link.springer.com/article/10.1007/BF00378331
"Methanol absorption rate through the human skin has been examined by the use of a modified direct method, and a value of 0.192 mg/cm2/min was determined."