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> And Gardasil is used in a much more limited population than the Covid vaccine will be. (It wouldn't be HN without a splash of pedantry; apologies in advance.

> And Gardasil is used in a much more limited population than the Covid vaccine will be. (It wouldn't be HN without a splash of pedantry; apologies in advance.) I'm curious what you mean by this. Women constitute slightly more than half of the population, no? There are probably billions of women at this point who have had Gardisil administered.

sokoloff 6y ago
HPV vaccination is now recommended for all adolescents.
refurb 6y ago
That's a fair question! So Gardasil is only approved for "girls and women 9 through 26 years of age". Plus there wasn't much expectation of use outside of Western countries initially since it's not cheap and there are likely higher priority vaccines in developing countries (i.e. do you spend dollars on this or meningitis vaccines?). Use is probably pretty broad now, ~10 years post-launch. Eventually they expanded the label to include "boys and men 9 through 26 years of age". So all in all, a relatively small slice of the population, where for the Covid vaccine, they're trying to get it approved for pretty much everybody.
- baryphonic 6y ago
  Oh, great point. I hadn't even thought about the fact that certain vaccines are approved only for certain age ranges.
Marsymars 6y ago
270 million doses worldwide to date, of those 100 million are in the USA. The full course is two or three doses depending on age, so that's somewhere between 90-135 million people fully covered. https://www.cancer.org/cancer/cancer-causes/infectious-agents/hpv/hpv-vaccine-facts-and-fears.html https://www.cancer.org/cancer/cancer-causes/infectious-agent... And it's not limited to women now. Different countries have it approved/covered for men of different ages. I (as a man) recently finished the full course, though I had to pay for it out of pocket.
travmatt 6y ago
Michael Douglas died from throat cancer contracted from HPV, as undoubtedly other men have. There’s reason for men to become vaccinated as well.
- Blackthorn 6y ago
  Michael Douglas is still very much alive, but it's still a good point that men should get vaccinated.
  - travmatt 6y ago
    I don’t know why I thought he passed for. But yea, hpv can lead to cancer in both genders.

sokoloff 6y ago

HPV vaccination is now recommended for all adolescents.

refurb 6y ago

That's a fair question! So Gardasil is only approved for "girls and women 9 through 26 years of age". Plus there wasn't much expectation of use outside of Western countries initially since it's not cheap and there are likely higher priority vaccines in developing countries (i.e. do you spend dollars on this or meningitis vaccines?). Use is probably pretty broad now, ~10 years post-launch. Eventually they expanded the label to include "boys and men 9 through 26 years of age". So all in all, a relatively small slice of the population, where for the Covid vaccine, they're trying to get it approved for pretty much everybody.

baryphonic 6y ago
Oh, great point. I hadn't even thought about the fact that certain vaccines are approved only for certain age ranges.

Marsymars 6y ago

270 million doses worldwide to date, of those 100 million are in the USA. The full course is two or three doses depending on age, so that's somewhere between 90-135 million people fully covered. https://www.cancer.org/cancer/cancer-causes/infectious-agents/hpv/hpv-vaccine-facts-and-fears.html https://www.cancer.org/cancer/cancer-causes/infectious-agent... And it's not limited to women now. Different countries have it approved/covered for men of different ages. I (as a man) recently finished the full course, though I had to pay for it out of pocket.

travmatt 6y ago

Michael Douglas died from throat cancer contracted from HPV, as undoubtedly other men have. There’s reason for men to become vaccinated as well.

Blackthorn 6y ago
Michael Douglas is still very much alive, but it's still a good point that men should get vaccinated.
- travmatt 6y ago
  I don’t know why I thought he passed for. But yea, hpv can lead to cancer in both genders.