Regardless of your judgement about self-experimentation, and regardless of the fact that a whitepaper is explicitly not a peer-reviewed journal article, the whi

Regardless of your judgement about self-experimentation, and regardless of the fact that a whitepaper is explicitly not a peer-reviewed journal article, the whitepaper [1] is a very interesting and carefully considered document. They argue throughout that multi-dose nasal vaccines are a severely underlooked avenue for localized immunization. A main criticism is that an untested vaccine might unintentionally enhance the actual disease. They argue that antibody-dependent enhancement (ADE) specifically is less likely because the immune response of the intranasal vaccine is limited to the mucosal tissue [2]. [1] https://radvac.org/wp-content/uploads/2020/07/White-Paper-SARS-CoV-2-vaccine-ver-2-3-2.pdf https://radvac.org/wp-content/uploads/2020/07/White-Paper-SA... [2] See [1] page 6