4 ms·
I generally agree people understand mouse models are imperfect. The issue here, is that you have to understand how they are imperfect if they have any value at
by lettergram 6y ago
I generally agree people understand mouse models are imperfect.
The issue here, is that you have to understand how they are imperfect if they have any value at all. In this case, doing drug research on a mouse model is fine. Unless the goal of that study is to see damage to organs or dna. Unfortunately, that’s what was not being controlled for or understood. Effectively, the DNA has more protection from damage in the lab micr used for models than normal mice or humans.
This implies most of our drug evaluations look better on paper than reality. Huge deal if true And there’s evidence (long term) to support this.
The reason it’s on the portal and Joe Rogan is no one in the scientific community is evaluating it (on the surface). What’s more baffling is working in and around this space, I can see the effects first hand (which I won’t dive into, for the same reason no one is saying anything about this in the scientific community).