3 ms·
Here's my link, from people working to promote evidence-based medicine: https://www.cebm.net/covid-19/masking-lack-of-evidence-with-politics/ https://www.cebm.n
by DanBC 6y ago
Here's my link, from people working to promote evidence-based medicine: https://www.cebm.net/covid-19/masking-lack-of-evidence-with-politics/ https://www.cebm.net/covid-19/masking-lack-of-evidence-with-...
From your link:
> (eg, reusable 12–16-layer cotton masks; pinteraction=0·090; posterior probability >95%, low certainty
That "low certainty" comes from GRADE. Low certainty in GRADE means "The true effect might be markedly different from the estimated effect". Masks may be very much better, or very much worse, than they estimate.
The Interpretation section says this:
> Robust randomised trials are needed to better inform the evidence for these interventions, but this systematic appraisal of currently best available evidence might inform interim guidance.
Which suggests to me that they want more and better evidence.
The end of the paper says this:
> Our comprehensive systematic review provides the best available information on three simple and common interventions to combat the immediate threat of COVID-19, while new evidence on pharmacological treatments, vaccines, and other personal protective strategies is being generated. Physical distancing of at least 1 m is strongly associated with protection, but distances of up to 2 m might be more effective. Although direct evidence is limited, the optimum use of face masks, in particular N95 or similar respirators in health-care settings and 12–16-layer cotton or surgical masks in the community, could depend on contextual factors; action is needed at all levels to address the paucity of better evidence. Eye protection might provide additional benefits. Globally collaborative and well conducted studies, including randomised trials, of different personal protective strategies are needed regardless of the challenges, but this systematic appraisal of currently best available evidence could be considered to inform interim guidance.
These sentences make me think the evidence isn't as strong as lots of people claim it is:
> while new evidence on [...] other personal protective strategies is being generated.
> Although direct evidence is limited
> action is needed at all levels to address the paucity of better evidence.
- nickthemagicman 6y agoEven in the 'evidence' the poster you're responding to says there's low evidence of effectiveness of mask usage.
- DanBC 6y agoPlease re-read my post. That's what I'm saying: that masks may work, but we have low quality evidence. We need more evidence, we need better evidence. dougmwne appears to be saying that masks work and that we know they work, but the link they provided doesn't support that claim.
- nickthemagicman 6y agoNo I was agreeing with you. Was pointing out that 'evidence' that the person you were replying to presented, said the certainty was 'low'.