3 ms·

Hard to get herd immunity from something you can get multiple times and which seem to be more deadly subsequent times.

• gnusty_gnurc 6y ago
  > Hard to get herd immunity from something you can get multiple times and which seem to be more deadly subsequent times. what's the evidence of this?
  • pfranz 6y ago
    I heard anecdotes of reinfection with worse symptoms on subsequent infections a few weeks ago; this looks to be the article [1]. I haven't heard widespread confirmation or studies showing this yet. [1] https://www.vox.com/2020/7/12/21321653/getting-covid-19-twice-reinfection-antibody-herd-immunity https://www.vox.com/2020/7/12/21321653/getting-covid-19-twic...
    • ericb 6y ago
      There are false negatives and positives in the tests. In Macaques they could not reinfect them, so this doesn't seem that likely.
  • anonuser123456 6y ago
    None AFAIK. Post infection, people seem to have robust neutralizing antibody responses and T cell immunity. Even if antibody responses are not measurably durable, latent B cell memory is _highly_ likely (e.g. antibody production restarts when the antigen is detected) Antibody dependent enhancement seems to be unlikely given that the SARS-COV-2 spike protein seems relatively stable. So once infected you are highly likely protected in the future. That doesn't mean you can't be reinfected and be contagious... just that rather than go into full blown ARDS/sepsis, you would have a mild cold.