3 ms·

Technically, you are really just waiting for the thermal inertia of the testing device. The reaction kinetics are really quite fast. During the last SARS outbr

Technically, you are really just waiting for the thermal inertia of the testing device. The reaction kinetics are really quite fast. During the last SARS outbreak, this sort of thing was proposed: https://pubs.rsc.org/en/Content/ArticleLanding/2011/AN/c1an15365j#!divAbstract https://pubs.rsc.org/en/Content/ArticleLanding/2011/AN/c1an1... ... to do 3 minute tests. I assume grant funding dried up, since who could guess that after 2 outbreaks that we'd have a 3rd?

drewwwwww 6y ago
the method described in the article uses a constant temperature of reaction. edited to add: https://en.wikipedia.org/wiki/Reverse_Transcription_Loop-mediated_Isothermal_Amplification https://en.wikipedia.org/wiki/Reverse_Transcription_Loop-med...
redis_mlc 6y ago
> I assume grant funding dried up, since who could guess that after 2 outbreaks that we'd have a 3rd? Yes, that's what I've read. Any US research scientists still working on SARS-1 after 2003 were told "you're on your own." Kudos to Canada for being as diligent as Taiwan in attacking COVID-19 - they remember it wiping out Toronto hospital staff in 2003. Check out the Youtube CBC channel for their impressive nation-wide mobilization. Makes you wonder wtf Chinese virology labs were doing for 20 years with coronavirus if they weren't working on a cure, doesn't it? (There's 40 labs total across China.)
- ethbro 6y ago
  > Makes you wonder wtf Chinese virology labs were doing for 20 years with coronavirus if they weren't working on a cure, doesn't it? (There's 40 labs total across China.) Like most things in a command economy, they worked on whatever was a political priority. I'd hazard to guess it wasn't a priority in the intervening years for the same reason there was little free market incentive to address it: yes, it's bad when it happens, but it doesn't happen that often. Ergo, they were probably just as starved of resources. The preexisting US effort was mostly funded through DARPA for the same reasons. https://www.darpa.mil/our-research https://www.darpa.mil/our-research (e.g. ADEPT, P3, Prometheus, PREPARE)

drewwwwww 6y ago

the method described in the article uses a constant temperature of reaction. edited to add: https://en.wikipedia.org/wiki/Reverse_Transcription_Loop-mediated_Isothermal_Amplification https://en.wikipedia.org/wiki/Reverse_Transcription_Loop-med...

redis_mlc 6y ago

> I assume grant funding dried up, since who could guess that after 2 outbreaks that we'd have a 3rd? Yes, that's what I've read. Any US research scientists still working on SARS-1 after 2003 were told "you're on your own." Kudos to Canada for being as diligent as Taiwan in attacking COVID-19 - they remember it wiping out Toronto hospital staff in 2003. Check out the Youtube CBC channel for their impressive nation-wide mobilization. Makes you wonder wtf Chinese virology labs were doing for 20 years with coronavirus if they weren't working on a cure, doesn't it? (There's 40 labs total across China.)

ethbro 6y ago
> Makes you wonder wtf Chinese virology labs were doing for 20 years with coronavirus if they weren't working on a cure, doesn't it? (There's 40 labs total across China.) Like most things in a command economy, they worked on whatever was a political priority. I'd hazard to guess it wasn't a priority in the intervening years for the same reason there was little free market incentive to address it: yes, it's bad when it happens, but it doesn't happen that often. Ergo, they were probably just as starved of resources. The preexisting US effort was mostly funded through DARPA for the same reasons. https://www.darpa.mil/our-research https://www.darpa.mil/our-research (e.g. ADEPT, P3, Prometheus, PREPARE)