3 ms·
Wait I’m a little confused. It seems like injecting people with an mRNA, which their cells then translate into an antigen that provokes an immune response, is a
by rotexo 6y ago
Wait I’m a little confused. It seems like injecting people with an mRNA, which their cells then translate into an antigen that provokes an immune response, is a very different technology from monoclonal antibodies. They are both related to the immune system, but mRNA vaccines are at least partially about stimulating polyclonal antibody production, as opposed to monoclonal antibodies. Can you articulate why you think mRNA vaccines were derived from monoclonal antibody work?
- dnautics 6y agoI just remember talks (I was at a cutting-edge immunology research center, The Scripps Research Institute in San Diego) about using mRNA vaccination in the 2007-2009 era to make monoclonal antibodies. Oddly, I can't find any publications from that era on it (but I can find a few papers from 2017-2019 using that exact methodology), so it appears that either i was mistaken, or it quietly pivoted to human vaccination as a target. It's really not possible for me to be mistaken about the timeframe, though, since I have been out of biology since 2015.