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The thing is someone else participating in that same study may read that and experience an unintended placebo/nocebo/antidote effect. You are not supposed to di
by anticensor 6y ago
The thing is someone else participating in that same study may read that and experience an unintended placebo/nocebo/antidote effect. You are not supposed to dicslose you are in such a clinical trial. The ancestrals misunderstood that as not telling the test subject that he is being tested. You could also neutralise that consent effect by making the group of consent broader than the group of study, by adding two more controls such that one group (reverse intervention group) takes a drug that acually worsens the disease (I see the possible objections, but this alone will make the study complete faster), and one takes just nothing (neutral group-those would be sent back by telling them they are diagnosed negative, but actual diagnosis will be recorded in their files), in addition to a placebo group.
- ageitgey 6y ago> You are not supposed to dicslose you are in such a clinical trial. They never asked that or made us sign anything to that effect. In this Phase 3 trial, they are measuring prevention of disease across ~10,000 people. They just want to see who tests positive for COVID and how sick they get. In this Phase, they aren't asking most groups about side effects or any subjective questions about symptom severity or anything like that where reading that someone was in a study would influence our opinion.