7 ms·
> The results have not been published in a peer-reviewed journal, nor has the full data been made available; so the BBC cannot confirm the claims made for the t
by topicseed 6y ago
> The results have not been published in a peer-reviewed journal, nor has the full data been made available; so the BBC cannot confirm the claims made for the treatment.
How are these claims any different than the few other ones heard over the last few weeks? They always sound incredibly promising..... and then nothing!
Is this different?
edit: typos
- BossingAround 6y agoSounds like this shouldn't even be a news story then.
- deelowe 6y agoSeveral new treatments have emerged. I just read ICU survival rates are are down nearly 20%.
- Gupie 6y agoWhich claims are these, could you give some examples, ones from reputable sources please.
- bamboozled 6y agoNot sure if I can give you sources, but have you followed the Oxford University vaccine story? It seems like they're working miracles while many other scientists are pretty skeptical if a vaccine can be found at all, or at least within such short time frames. This is anecdotal, but I do agree with the OP, there is a lot of conflicting information available.
- Gupie 6y agoWe will find out eventually whether the Oxford University vaccine works or becomes an example of "and then nothing". But it is definitely not a "and then nothing" yet.
- mathw 6y agoSeveral vaccine projects have reported good stimulation of antibody production in trials. The big problem is that we don't yet know what kind of immunity that may provide or how long it might last. But it seems getting people to produce antibodies without making them ill is extremely possible.
- ethbro 6y agoFrom the Moderna Phase I results published recently [1], I'd point out that most vaccine candidates are also performing antibody challenges and T-cell counting, to better characterize the effective immune response generated [2], beyond antibody production. [1] https://www.nejm.org/doi/full/10.1056/NEJMoa2022483 https://www.nejm.org/doi/full/10.1056/NEJMoa2022483 [2] Via assessment methods in the above: "pseudotyped lentivirus reporter single-round-of-infection neutralization assay (PsVNA) and by live wild-type SARS-CoV-2 plaque-reduction neutralization testing (PRNT)" & "T-cell responses against the spike protein were assessed by an intracellular cytokine–staining assay, performed on specimens collected at days 1, 29, and 43"
- nl 6y agoThere are many vaccine projects showing promising results. > there is a lot of conflicting information available That's the nature of science. There is conflicting information because it is unknown what works yet. There are many approaches that show promise.. until they don't.
- topicseed 6y agohttps://www.nytimes.com/interactive/2020/science/coronavirus-drugs-treatments.html https://www.nytimes.com/interactive/2020/science/coronavirus...
- chvid 6y agoWhat is worse this is a public traded company: https://markets.ft.com/data/equities/tearsheet/summary?s=OMY:FRA https://markets.ft.com/data/equities/tearsheet/summary?s=OMY... Up more than 200% today!!!
- gertrunde 6y agoAlso mentioned in the article: "Stock market rules mean Synairgen is obliged to report the preliminary results of the trial."
- londons_explore 6y agoWhich rules exactly? Plenty of of publicly traded companies keep R&D projects secret...
- weego 6y agoWe're specifically talking about clinical trials.
- bluGill 6y agoThere comes a time when you can no longer keep something secret even if you try. The next step in getting this approved requires that some people be told about this that you must assume will not keep it secret (ie a journal that goes to libraries for anyone to read). Thus at this point they have to tell everyone who might invest, that way they can't be accused of telling their friends.
- dmix 6y agoTo be fair the stock wasn't worth much before today... It's far easier to get big sounding percentages with small numbers.
- system2 6y agoStill, if you put 100k, you get 200k back.
- vmception 6y agoOne key component of getting peer review is by peers knowing about it.
- dotancohen 6y agoThere are forums for that. Not internet forums, "forum" in the original sense of the word. A public broadcast to the masses (the B in BBC) is not the forum for notifying peers in a professional field.
- vmception 6y agoand yet, it also notifies peers in a professional field.
- whymauri 6y agoI've never published a BBC (or any journal) article before publishing a paper. As far as I know, the reviewers at Springer Nature could not care less if there's a press release attached to your manuscript, and some reviewers in medicinal journals would prefer groups don't publicize on media like Twitter to avoid biased reviews. I must have just missed the "mass press release" portion of peer review.
- sydd 6y agoYea. Releasing such articles is irresponsible journalism, I'd put it in the same category as fear-mongering.
- monkeynotes 6y agoBBC is as much clickbait as any. The days of actual journalism at the BBC pretty much died off a number of years ago.
- bkanber 6y ago> Weeks I'm sorry, but even with things getting rushed through by regulatory agencies, you cannot expect prelim results to convert to treatments in only a matter of weeks.
- baybal2 6y ago> How are these claims any different than the few other ones heard over the last few weeks? They always sound incredibly promising..... and then nothing! Cubans, and few other ex-Eastern Bloc countries were peddling interferons as miracle cures in the past. The reality showed a big part of it being a cargo cult science, except for a few cases when it wasn't, and they actually worked. The same thing was for the bacteriophage medicine from ex-USSR coutnries. It indeed works, and it is in deed very arcane to most of Western antibiotic researchers, but it's nowhere near the "miracle cure" they peddle it as.