4 ms·
Rubbish comment. The paper studies many things and found iron metabolism is a common factor for aging. "Haem synthesis declines with age and its deficiency lea
by 1996 6y ago
Rubbish comment. The paper studies many things and found iron metabolism is a common factor for aging.
"Haem synthesis declines with age and its deficiency leads to iron accumulation, oxidative stress, and mitochondrial dysfunction. In turn, iron accumulation helps pathogens to sustain an infection, which is in line with the known increase in infection susceptibility with age. In the brain, abnormal iron homeostasis is commonly seen in neurodegenerative diseases such as Alzheimer’s and Parkinson’s disease and multiple sclerosis"
Also FYI in the title "Multivariate genomic scan implicates novel loci and haem metabolism in human ageing", haem implies iron.