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Something to consider and also something not discussed in the article: it's very possible that sars-cov-2 can directly infect neurons directly considering the e
by eganist 6y ago
Something to consider and also something not discussed in the article: it's very possible that sars-cov-2 can directly infect neurons directly considering the expression of ace2 receptors across them.
https://www.biorxiv.org/content/10.1101/2020.04.07.030650v1 https://www.biorxiv.org/content/10.1101/2020.04.07.030650v1
So beyond the risk of kidney failure stemming from damaged cardiovascular tissue debris jamming up nephrons (as well as potential direct kidney infection by the virus) and beyond the risk of stroke from the uptick of platelets and the redistribution of the marrow cells which produce them across the body (somehow. I can't find the research that identified this), there's also the risk that the virus is actually directly attacking neurons.
Not really a surprise considering how common ACE2 receptors are.
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I'm not a doctor. Not an epidemiologist either. Please fact-check me if I'm wrong.
- sradman 6y agoThat paper answers my first question, does neurological tissue have ACE2 receptors. The damage can also be a side-effect of oxygen deprivation. The existence of ACE2 receptors in the brain begs the question of how the SARV-CoV-2 virus crosses the blood-brain barrier. IIRC, dental surgery has been correlated to pathogens crossing the barrier. I wonder if that is a key factor here as well.