6 ms·

Scientists uncover first atomic structure of Epstein-Bar virus nucleocapsid

55 points by dnetesn 6y ago

avmich 6y ago
> Provided by Chinese Academy of Sciences Is it trustworthy?
- analog31 6y ago
  In my view, hopefully that question can be replaced with: Is it reproducible? The method they mentioned, Cryo-EM, is also how we've got those amazing 3d pictures of the novel coronavirus. They mentioned that preparing a good sample was a challenge, but it shouldn't be insurmountable for someone else to repeat that part of the experiment.
  - avmich 6y ago
    No, the intent of the question was: do we still have trust into scientific information coming from China? We know that China government closely controls many aspects of life in their interests, so should we consider this an exception? Or, instead, should we wait for publication in a trustworthy source about "we were able to successfully repeat experiments, earlier reported from China, which demonstrate..."? I guess the matter of trust is for everybody to decide by themselves.
    - analog31 6y ago
      Indeed, perhaps I should have said it a bit differently. There's certainly a potential issue with government influence over scientific research. But there's also an issue with any preliminary finding, and the same solution could address both issues. I considered the important finding is not necessarily the images, but the recipe for preparing a sample of the virus. If this recipe works, labs with better equipment or better techniques should be able to produce even better data. If the recipe doesn't work, it will be quickly apparent. There are known histories of government influence over science research with unhappy endings, such as the Lysenko affair, and probably global warming research in the US. Countries know that spewing out false scientific knowledge, if it's a solution for any problem, is a short term one. The Chinese government still has an interest in developing a good reputation in science. At least that's my take.
    - toast0 6y ago
      > Or, instead, should we wait for publication in a trustworthy source about "we were able to successfully repeat experiments, earlier reported from China, which demonstrate..."? I mean, shouldn't we wait for that always rather than reporting unreproduced findings to people other than those who might reproduce it?
      - analog31 6y ago
        I think so long as people understand how science works, or the journalists provide some explanatory insight about it, reporting interesting science news to the public should be OK. Scientists tend to be skeptical of systems that decide who should have access to information before others. Most findings are unreproduced. It usually takes someone with a reason to be interested, to reproduce a study.
- ggm 6y ago
  As trustworthy as the US equivalent. (I've met and worked with members of the CAS in ICT and they are people of high integrity and competent leaders in their field of science)
  - avmich 6y ago
    That's great, but for how long should we trust our previous experience regarding this? With plenty of recent examples from a relatively tightly government controlled country should we worry that a publication may pursue unusual goals?
    - haecceity 6y ago
      Clearly you know the answer to these questions. Why even ask. Just be confident say what you feel.
- ckocagil 6y ago
  Generally, national academies of sciences are very highly regarded. In the case of CAS, Wikipedia says that they've been the number 1 institute on Nature Index for years. https://www.nature.com/articles/d41586-020-01230-x https://www.nature.com/articles/d41586-020-01230-x
digi59404 6y ago
Hopefully this helps them find a cure/treatment. Most people don’t have complications from this virus, I am one of the few that did. Now, every so often when I get the flu or a cold. Or in general my immune system gets weaker, lack of sleep, etc. I get another round of mononucleosis. My throat swells shut, I get ridiculous fatigue, and I get swelling and soreness pretty much all over. I’m then doomed to a week of bed rest and water+pudding+soap. I fear that these complications will arise and make other illnesses worse as they do with the flu and colds. I really fear this combine with covid will do me in. I guess we’ll see.
- zerubeus 6y ago
  The virus is also the direct cause of many Cancers of the immune system, it causes more than 500k cancer worldwide most of them Lymphomas
  - digi59404 6y ago
    How poetic. My fiancée has chronic neutrophilic leukemia, or is suspected to have I should say. As there’s no testing or treatment, you can only see the symptoms and body’s reaction to the illness and conclude. We see a specialist every 6 months for the rest of her life to monitor her blood and ensure it doesn’t progress. For the rest of her life. Here’s to hoping I go out in a blaze of glory as opposed to cancer, caused by this virus, that was given to me by my cheating ex.
    - zerubeus 6y ago
      Very tough, but just so you don't overthink this too much, we all end up catching this Virus, in the United States, about half of all five-year-old children and about 90% of adults have evidence of previous infection, still there's only 200,000 cancer cases per year are thought to be attributable to EBV
- tomcam 6y ago
  Sounds dreadful. My best to you. What is the soap for?

55 points by dnetesn 6y ago

avmich 6y ago

> Provided by Chinese Academy of Sciences Is it trustworthy?

analog31 6y ago
In my view, hopefully that question can be replaced with: Is it reproducible? The method they mentioned, Cryo-EM, is also how we've got those amazing 3d pictures of the novel coronavirus. They mentioned that preparing a good sample was a challenge, but it shouldn't be insurmountable for someone else to repeat that part of the experiment.
- avmich 6y ago
  No, the intent of the question was: do we still have trust into scientific information coming from China? We know that China government closely controls many aspects of life in their interests, so should we consider this an exception? Or, instead, should we wait for publication in a trustworthy source about "we were able to successfully repeat experiments, earlier reported from China, which demonstrate..."? I guess the matter of trust is for everybody to decide by themselves.
  - analog31 6y ago
    Indeed, perhaps I should have said it a bit differently. There's certainly a potential issue with government influence over scientific research. But there's also an issue with any preliminary finding, and the same solution could address both issues. I considered the important finding is not necessarily the images, but the recipe for preparing a sample of the virus. If this recipe works, labs with better equipment or better techniques should be able to produce even better data. If the recipe doesn't work, it will be quickly apparent. There are known histories of government influence over science research with unhappy endings, such as the Lysenko affair, and probably global warming research in the US. Countries know that spewing out false scientific knowledge, if it's a solution for any problem, is a short term one. The Chinese government still has an interest in developing a good reputation in science. At least that's my take.
  - toast0 6y ago
    > Or, instead, should we wait for publication in a trustworthy source about "we were able to successfully repeat experiments, earlier reported from China, which demonstrate..."? I mean, shouldn't we wait for that always rather than reporting unreproduced findings to people other than those who might reproduce it?
    - analog31 6y ago
      I think so long as people understand how science works, or the journalists provide some explanatory insight about it, reporting interesting science news to the public should be OK. Scientists tend to be skeptical of systems that decide who should have access to information before others. Most findings are unreproduced. It usually takes someone with a reason to be interested, to reproduce a study.
ggm 6y ago
As trustworthy as the US equivalent. (I've met and worked with members of the CAS in ICT and they are people of high integrity and competent leaders in their field of science)
- avmich 6y ago
  That's great, but for how long should we trust our previous experience regarding this? With plenty of recent examples from a relatively tightly government controlled country should we worry that a publication may pursue unusual goals?
  - haecceity 6y ago
    Clearly you know the answer to these questions. Why even ask. Just be confident say what you feel.
ckocagil 6y ago
Generally, national academies of sciences are very highly regarded. In the case of CAS, Wikipedia says that they've been the number 1 institute on Nature Index for years. https://www.nature.com/articles/d41586-020-01230-x https://www.nature.com/articles/d41586-020-01230-x

digi59404 6y ago

Hopefully this helps them find a cure/treatment. Most people don’t have complications from this virus, I am one of the few that did. Now, every so often when I get the flu or a cold. Or in general my immune system gets weaker, lack of sleep, etc. I get another round of mononucleosis. My throat swells shut, I get ridiculous fatigue, and I get swelling and soreness pretty much all over. I’m then doomed to a week of bed rest and water+pudding+soap. I fear that these complications will arise and make other illnesses worse as they do with the flu and colds. I really fear this combine with covid will do me in. I guess we’ll see.

zerubeus 6y ago
The virus is also the direct cause of many Cancers of the immune system, it causes more than 500k cancer worldwide most of them Lymphomas
- digi59404 6y ago
  How poetic. My fiancée has chronic neutrophilic leukemia, or is suspected to have I should say. As there’s no testing or treatment, you can only see the symptoms and body’s reaction to the illness and conclude. We see a specialist every 6 months for the rest of her life to monitor her blood and ensure it doesn’t progress. For the rest of her life. Here’s to hoping I go out in a blaze of glory as opposed to cancer, caused by this virus, that was given to me by my cheating ex.
  - zerubeus 6y ago
    Very tough, but just so you don't overthink this too much, we all end up catching this Virus, in the United States, about half of all five-year-old children and about 90% of adults have evidence of previous infection, still there's only 200,000 cancer cases per year are thought to be attributable to EBV
tomcam 6y ago
Sounds dreadful. My best to you. What is the soap for?