3 ms·

But I don’t think scientists think that previous common cold exposure actually makes you immune? The hypothesis I heard is that this immune response due to pre

by arrrg 6y ago

But I don’t think scientists think that previous common cold exposure actually makes you immune? The hypothesis I heard is that this immune response due to previous common cold corona virus exposure could explain the high proportion of asymptomatic cases or cases with very mild symptoms. Those are already priced in, so we already know about their existence, it would just be an explanation as to why they exist. I‘m also not sure why you think that even neighboring and very similar countries are so wildly different based on wildly different levels of pre-existing immunity. That doesn’t seem very plausible. Why should, say, Germany and Italy be so different? Or Germany and France?

jdminhbg 6y ago
> But I don’t think scientists think that previous common cold exposure actually makes you immune? That's the subject of the paper being discussed, it's worth going back and looking at it. The researchers demonstrated T-cell reactivity against it not just in blood from people who had SARS-Cov-1/2 but those who had neither. So something else is going on -- maybe one of the common cold coronaviruses, maybe some other infective but not dangerous coronavirus, maybe something else. > I‘m also not sure why you think that even neighboring and very similar countries are so wildly different based on wildly different levels of pre-existing immunity. That doesn’t seem very plausible. Why should, say, Germany and Italy be so different? Or Germany and France? Since we don't even know the source of this pre-existing immunity, much less how it varies between countries, it's impossible to say. But it's clear that there are many differences between what happens in countries that aren't just lockdown timing/severity. Immunity, density, demographics, climate, sheer luck, etc.

3 ms·

But I don’t think scientists think that previous common cold exposure actually makes you immune? The hypothesis I heard is that this immune response due to pre

by arrrg 6y ago

jdminhbg 6y ago
> But I don’t think scientists think that previous common cold exposure actually makes you immune? That's the subject of the paper being discussed, it's worth going back and looking at it. The researchers demonstrated T-cell reactivity against it not just in blood from people who had SARS-Cov-1/2 but those who had neither. So something else is going on -- maybe one of the common cold coronaviruses, maybe some other infective but not dangerous coronavirus, maybe something else. > I‘m also not sure why you think that even neighboring and very similar countries are so wildly different based on wildly different levels of pre-existing immunity. That doesn’t seem very plausible. Why should, say, Germany and Italy be so different? Or Germany and France? Since we don't even know the source of this pre-existing immunity, much less how it varies between countries, it's impossible to say. But it's clear that there are many differences between what happens in countries that aren't just lockdown timing/severity. Immunity, density, demographics, climate, sheer luck, etc.