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You can't even send from a normal alias in Office 365, so I'd be shocked if you'll be able to send from these '+' aliases.

• inanutshellus 6y ago
  Wow, that sucks. I honestly don't see how that would work. Like, how would you unsubscribe to a mailing list? Most these days let you click a link rather than reply with "unsubscribe" but still... I've had multiple occasions where contact /to/ a business needed to come from the email address I used to sign up with their service (automatic correlation to users I guess). One particular exchange was particularly painful. Every email I sent was, I assume, routed to a new customer queue. Every email that I sent from my non-+ alias was delayed by days and then dealt with by an unhelpful "we don't recognize this email address". It was very painful and it was all because I used a + alias as my supplied email address but kept forgetting to use it as my 'from' address. Had I not had the ability to set it as my 'from' I'd probably have stopped using + aliases entirely.