2 ms·

I dispute your characterization that people had no clue. https://en.wikipedia.org/wiki/Siege_of_Fort_Pitt#Biological_warfare https://en.wikipedia.org/wiki/Sieg

• dudul 6y ago
  But that happened in the 18th century though, by then of course, empirical observation had played its role and a few people tried to weaponize it. I'm pretty sure accidental contamination during the 2 preceding centuries had already caused a massive decline in population.