3 ms·
Good Enzymes are Hard to Make (de novo computational protein & enzyme design)
- bbgm 18y agoOur understanding of the physics of protein folding and protein design is still so limited that I continue to be amazed at the results that David Baker (and some others) can get. I am still skeptical about how general these methods are, what the false positive (and false positive) rates are and how much specificity we can design into our systems