4 ms·

If you have 23andme, the exact allele is not on the chip. However, a different allele is strongly associated with the region: https://you.23andme.com/tools/dat

by herf 6y ago

If you have 23andme, the exact allele is not on the chip. However, a different allele is strongly associated with the region: https://you.23andme.com/tools/data/?query=rs10490770&filter_by_platforms=true https://you.23andme.com/tools/data/?query=rs10490770&filter_... The major A/A variant is listed as T/T on 23andme. If you have a result other than "T/T", you're likely to be in the high-risk group. refs: https://www.snpedia.com/index.php/Rs11385942 https://www.snpedia.com/index.php/Rs11385942 [not on 23andme] https://www.snpedia.com/index.php/Rs10490770 https://www.snpedia.com/index.php/Rs10490770

modeless 6y ago
That 23andme link doesn't work for me, it says no genes or markers found for rs10490770.
- drocer88 6y ago
  Try this : https://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?do_not_redirect&rs=rs10490770 https://www.ncbi.nlm.nih.gov/projects/SNP/snp_ref.cgi?do_not... This breaks down the population frequencies. Of note: the HAPMAP AA frequencies: Gujarati Indians in Houston Texas : 38% , African ancestry in Southwest USA: 4%. It is absent in Chinese, Japanese and sub-saharan Africans.
- helpme23 6y ago
  I couldn’t get it to work either, did anyone figure out how to view it on there?
LegitShady 6y ago
This is actually the first time the 23andme results did anything useful for me. Thank!
- helpme23 6y ago
  How did you get it to pull on 23 and me. I have more Neanderthal variants than 99% of users so I’m super interested. Thank you for any help you can provide.
wcoenen 6y ago
Thanks for sharing these pointers! A caveat for those who don't click through to the snpedia references: the "strongly associated region" only correlates well for Caucasians.