Svante Pääbo , one of the preprint authors, is the head of the Max Planck Institute for Evolutionary Anthropology. https://en.wikipedia.org/wiki/Svante_P%C3%A

Svante Pääbo , one of the preprint authors, is the head of the Max Planck Institute for Evolutionary Anthropology. https://en.wikipedia.org/wiki/Svante_P%C3%A4%C3%A4bo https://en.wikipedia.org/wiki/Svante_P%C3%A4%C3%A4bo . He is known for his work in assembling the Neanderthal and Denisovan genomes. Of particular note in this paper, the genetic variants in the genomic locus discussed are found in 30% of South Asian populations: India and Bangladesh. The highest frequency occurs in Bangladesh, where more than half the population (63%) carries at least one copy of the Neandertal risk variant and 13% is homozygous for the variant. The risk variant is 8% frequency in Europe. The hg19 location of Genetic variants in LD (r2>0.99) with rs11385942 in Eurasian populations can be viewed here at the UCSC genome browser: https://genome.ucsc.edu/cgi-bin/hgTracks?db=hg19&position=chr3%3A45871908%2D45909024 https://genome.ucsc.edu/cgi-bin/hgTracks?db=hg19&position=ch... The genome wide association study that points out this area of the genome is here : https://www.nejm.org/doi/full/10.1056/NEJMoa2020283 https://www.nejm.org/doi/full/10.1056/NEJMoa2020283 . At this "locus 3p21.31, the association signal spanned the genes SLC6A20, LZTFL1, CCR9, FYCO1, CXCR6 and XCR1." Three of the genes, XCR1 CXCR6 CCR9, are involved with chemokine receptor activity and G-protein coupled chemoattractant receptor activity.