3 ms·

New evidence has been coming out that HCQ + azithromycin is not a bust. Not a magic bullet, but a very decent mitigation. https://www.ijidonline.com/article/S1

• belltaco 6y ago
  That's an observational study, which don't turn to be true all the time. The randomized controlled trials have shown it's a bust.
  • jonhohle 6y ago
    From the author: > “Our dosing also differed from other studies not showing a benefit of the drug. And other studies are either not peer reviewed, have limited numbers of patients, different patient populations or other differences from our patients.”
    • belltaco 6y ago
      Also from the author: >However, our results should be interpreted with some caution and should not be applied to patients treated outside of hospital settings. Our results also require further confirmation in prospective, randomized controlled trials that rigorously evaluate the safety, and efficacy of hydroxychloroquine therapy for COVID-19 in hospitalized patients. The main issue is that retrospective studies like this show promise all the time and then frequently fizzle out in RCTs. If you're not used to reading studies they will sound very promising, someone who's been reading studies for 10 years will understand why this and the French studies that started the hype early on can be very misleading.