Slightly off topic: Does somebody have a recommendation of a toolkit or library for simple data entry and display with Python? Basically I want to replace Excel

Slightly off topic: Does somebody have a recommendation of a toolkit or library for simple data entry and display with Python? Basically I want to replace Excel/Calc for mostly tabular data, because I hate the programming and data access model (e.g. instead of writing B$8 or sum(A9:A23) I would like to have map/reduce function with reasonable variable names). But the presentation and entry speed is much better with spreadsheet software, than when using some ad-hoc plain text format for simple parsing with python.