> As bad as animal (and human) studies and trials can be, the beauty of them is we don't really have to know how or why things work, we can just do the thing an

> As bad as animal (and human) studies and trials can be, the beauty of them is we don't really have to know how or why things work, we can just do the thing and if the results are good, we have a new treatment. If you didn't have at least a broad idea of why something might work, you would most likely never have "done the thing". You need to narrow the search space. Simulations can help here.