Has anyone considered designing an IT infrastructure from the ground up that would be maximally resistant to ransom ware? I think past generations are excused

Has anyone considered designing an IT infrastructure from the ground up that would be maximally resistant to ransom ware? I think past generations are excused for not preparing this, simply because it was theoretical. It is real now. So designing systems that assume some part will be captured eventually, and then work to minimize that before they are even deployed, would be timely now.