However, you will get enormously higher valuations - literally four to ten times or more - if you have the right connections in Silicon Valley. And you will get

However, you will get enormously higher valuations - literally four to ten times or more - if you have the right connections in Silicon Valley. And you will get acquired more readily (very likely because of those same connections) in Silicon Valley. Until/unless companies outside the Bay Area get those same sorts of valuations - and largely they won't because the angel/VC infrastructure isn't there - it makes way more sense to move to Palo Alto.