4 ms·
The way they presented their oddball claims definitely don't belong . They didn't present their statistics and sample size, they got what is almost certainly a
by vikramkr 6y ago
The way they presented their oddball claims definitely don't belong . They didn't present their statistics and sample size, they got what is almost certainly a false positive, and instead of acknowledging any of that, they decided to draw a conclusion and present the idea that the virus was spreading in Barcelona in early 2019. The responsible thing to do is to retest the samples, check for sources of contamination, figure out why only two of the five primers are positive. And, check with colleagues and the literature to find out if the primers have a known false positive rate and if that could be it. And, go ahead and sequence the results of our PCR to see if you can get covid sequences out of it. And if you can't figure out how that result came out after all of that, present that with the clear disclaimer that this doesn't make sense in the context of existing data, detail what you went through to test that finding, and clearly delineate the uncertainty and call for further investigation. This is just sloppy science.
- hcknwscommenter 6y ago"And, go ahead and sequence the results of our PCR to see if you can get covid sequences out of it. " Absolutely. If your hypothesis and/or data flies in the face of all (other) available data, you should leave no stone unturned to prove you are right. Actually showing that the amplified material is in fact COVID sequence would be just one very simple step in doing that. It's been a while, but the cost is about $200 and the time is about 24 hrs to purify and sequence an amplified product? It's quite telling that they didn't bother and/or didn't report the (likely negative result).
- vikramkr 6y agoless than $200 and more than 24 hours if they're outsourcing it to any of the many sequencing providers out there. Still, less than a week total