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We've been dosing people with hydroxychloroquine for malaria for years so it would be very surprising if it suddenly turned dangerous. It's pretty clear at thi

We've been dosing people with hydroxychloroquine for malaria for years so it would be very surprising if it suddenly turned dangerous. It's pretty clear at this point from a number of randomized trials that giving it to people who have developed Covid-19 isn't particularly useful. It's still possible that it might be useful prophylacticly, there's been some promising non-RCT studies coming out of India and at least one RCT underway, but I'm not sure I'd bet on it. EDIT: And to be clear the Indian studies suggested you wanted to be taking it for weeks before first exposure to SARS-2.

wbl 6y ago
It's always dangerous. It has a black box warning for arrhythmia.
Nursie 6y ago
> it would be very surprising if it suddenly turned dangerous https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/009768s037s045s047lbl.pdf https://www.accessdata.fda.gov/drugsatfda_docs/label/2017/00... Just because something is a useful medicine that's been given for a while doesn't mean it can't also have serious side effects, some of which could conceivably exacerbate Sars-CoV-2. Or not, there's no evidence that it does. But a lot of medicines are "dangerous", including Plaquenil, particularly if applied for the wrong circumstance or given to people with contraindications.