3 ms·
Maybe the contact cleaner helped dissolve and transport the LSD into his skin?
by annoyingnoob 6y ago
Maybe the contact cleaner helped dissolve and transport the LSD into his skin?
- girvo 6y agoA technician in Dave Nichol's lab tried this with DMSO, a well-known and much more potent solvent for attempting this: > And yesterday I was talking to Nick Sand, and Nick said, "I made a solution of LSD in DMSO…" -- DMSO (dimethyl sulfoxide) is a chemical that greatly enhances absorption of other chemicals through the skin -- he says, "…I painted it on my skin. Nothing happened." A concentrated solution and nothing happened! How did this very meticulous Swiss chemist get the LSD into his body? I don't know.
- gavinray 6y agoHaha, it's not even that DMSO is just a solvent, that garlicky stuff is a magic potion for turning things into transdermals. Testosterone ester crystals? Not bioavailable at all, but put it in some DMSO and lather on and you're in business. It works for, astoundingly, most anything. And if there's any man you're to trust on the pharmacokinetics of psychedelics, it would be Nichols, our co-founding father of all modern phenethylamine, tryptamine and lysergamide knowledge. Complete hoopla I say.
- girvo 6y agoAnd yet amusingly my initial comment is downvoted and most of the comments here are arguing with me regarding it. LSD is not active transdermally!