> Since I don't have anything to be depressed about I think this is a case where a word is used in two different ways and it is important to be clear to keep t

> Since I don't have anything to be depressed about I think this is a case where a word is used in two different ways and it is important to be clear to keep the intended meaning clear. "I'm depressed that she turned me down" is a very different kind of depression than clinical depression. There doesn't have to be any external negative condition to cause someone to have clinical depression. As far as I know, when people talk about using ketamine to help depressed people, they are talking about hard to treat clinical depression, not the short term state of disappointment or sadness that people also call depression.