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Insulin does not lead to increased weight gain. If this approach does work, it's because it's a roundabout way of eating lower calorie foods and thus lowering d
by ryeguy 6y ago
Insulin does not lead to increased weight gain. If this approach does work, it's because it's a roundabout way of eating lower calorie foods and thus lowering daily caloric intake.
- jacobedawson 6y agoAfaiu insulin in combination with elevated blood glucose levels specifically does lead directly to weight gain - it's like a vicious cycle in that high blood sugar = increased insulin levels = excess glucose is stored as fat.
- mdomans 6y agoNo. I can elaborate but generally it's the glucose that stimulates the insulin release (the pancreas has glucose receptors). Weight gain IS NOT driven by insulin or glucose. You can put someone on euglycemic clamp literally pumping him with insulin and glucose and he won't get fat from that. He will hover start storing fat IF we give him too much glucose for his needs. Frankly, if you were a very mad you could theoretically put yourself on insulin/protein infusion to lose fat. Idea being that insulin will drop your blood glucose (via insulin-dependant glucose transporter translocation) forcing liver to balance that out. When liver runs out of stored glucose it will start breaking down fat. The downside of that is that eventually muscles won't store more glucose (you'd somehow need to get rid of that) and the risk of dying is pretty high.
- tom_mellior 6y ago> high blood sugar = increased insulin levels = excess glucose is stored as fat. As opposed to? What would happen to excess glucose otherwise? Your body won't just excrete it, will it?