CPython, the reference implementation, interprets Python. PyPy interprets and JIT compiles Python, and more exotic things like Cython and Grumpy statically comp

CPython, the reference implementation, interprets Python. PyPy interprets and JIT compiles Python, and more exotic things like Cython and Grumpy statically compiles Python (often through another, intermediate language like C or Go). Node.js, using V8, interprets and JIT compiles JavaScript. Although note that, while Node.js is fast relative to Python, it's still pretty slow. If you're writing web-stuff, I'd recommend Go instead for casually written, good performance.