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Zebrafish study: The researchers introduce a fusion protein into the cell which combines two proteins: (i) protein responsible for axon growth and (ii) photoac
by seesawtron 6y ago
Zebrafish study:
The researchers introduce a fusion protein into the cell which combines two proteins: (i) protein responsible for axon growth and (ii) photoactivatable (Rac1) protein that is responsible for sensing light (found in plants). By giving a light stimulus, they could make the axon follow the path illuminated by light. This was also shown to work for regenrating axons that were genetically defective. This could potentially allow study of long range projections of axons in a non-invasive manner.
Orignal paper: https://www.cell.com/developmental-cell/fulltext/S1534-5807(20)30398-1 https://www.cell.com/developmental-cell/fulltext/S1534-5807(...