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My understanding is that they achieve "double-blind" by giving everybody either a low dose or high dose. So everybody gets mushrooms, and the effect is based on
by qntty 6y ago
My understanding is that they achieve "double-blind" by giving everybody either a low dose or high dose. So everybody gets mushrooms, and the effect is based on the difference between a low dose and high dose. Experimenters don't know the dose that a subject gets, and subjects don't know that there is a difference in the dose they could get, so they can't try to guess what dose they got. It does tend to be obvious to the experimenters who got which dose when it kicks in though.
- young_unixer 6y ago> subjects don't know that there is a difference in the dose they could get, so they can't try to guess what dose they got. Do subjects really believe this? "Even though most trials are done with placebo groups I'm sure this one will be different"
- qntty 6y agoBoth groups are told that they will get psilocybin and they do. Maybe they guess there's a placebo group, but when it starts to kick in, they figure it wasn't them.