I think that pattern scales really well up to a medium-sized startup. I stick those two (webserver/static content and API) plus a database in a docker-compose

I think that pattern scales really well up to a medium-sized startup. I stick those two (webserver/static content and API) plus a database in a docker-compose file, and put all three plus a frontend in a single repo. That feels like the sweet spot of "separate but integrated" for my work.