For a long time, it was the cameras. We couldn't get smaller things into focus and still preserve high-resolution images. Now that the camera problem has been s

For a long time, it was the cameras. We couldn't get smaller things into focus and still preserve high-resolution images. Now that the camera problem has been solved with CMOS detectors, the next problem is likely going to be the contrast-transfer function [1]. If we can solve that (such as with an energy filter, as I suspect the authors of this paper used), we can get smaller and smaller samples in focus without losing high resolution information from the electron scattering. [1] https://www.youtube.com/watch?v=mPynoF2j6zc https://www.youtube.com/watch?v=mPynoF2j6zc