3 ms·
3.5Å cryo-EM structures have existed for some time. The important thing coming down under 2Å or so, is that it drastically improves the quality of the molecular
by l33tman 6y ago
3.5Å cryo-EM structures have existed for some time. The important thing coming down under 2Å or so, is that it drastically improves the quality of the molecular dynamics simulations you build of these structures.
- natechols 6y agoI'm skeptical of molecular dynamics and docking studies... but the ability to clearly resolve bound drug molecules, or host-pathogen interactions, is very valuable indeed.