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Agree. On science taking its time, one thing that baffles me is that in the US and the UK, HCQ trials are only starting, as we reach the tail of this pandemic.
by cm2187 6y ago
Agree. On science taking its time, one thing that baffles me is that in the US and the UK, HCQ trials are only starting, as we reach the tail of this pandemic. Would someone know what is the rationale for waiting so long?
- noelsusman 6y agoThey're not only starting now, they've been going since early February. This one just finished: https://www.nejm.org/doi/full/10.1056/NEJMoa2016638 https://www.nejm.org/doi/full/10.1056/NEJMoa2016638. It found no preventive effect. Other trials are looking at treatment effectiveness.
- garmaine 6y agoSigh. They were not giving zinc supplements. It’s really frustrating that the theorized mechanism of HCQ effectiveness as a prophylactic is its ability to transport zinc across cell walls (zinc interrupts the viral RNA replication), yet these trials don’t include zinc supplements.
- lbeltrame 6y ago> Sigh. They were not giving zinc supplements. Check the supplementary data. There were confounding factors, but a group of patients took zinc, and there is no difference between the two groups. Bear in mind that this study has no say on the use as a treatment.
- garmaine 6y agoThanks, that's good to know.
- cm2187 6y agoWell, a first victim of the loss of credibility of these publications. How do I know this study is more serious than the lancet study?