3 ms·

Lancet is different than other scientific journals - it is the pinnacle. Publishing something so bad is reputationally harmful in ways that might not be so seve

Lancet is different than other scientific journals - it is the pinnacle. Publishing something so bad is reputationally harmful in ways that might not be so severe in other cases. Of course, this isn't the first incident Lancet has had (recalling the Wakefield incident in particular), but it should not be excused - just as Wakefield shouldn't - and should be judged rather harshly.

salmon30salmon 6y ago
Edit: As OP mentioned, this is the "wakefield incident" Don't forget, The Lancet is also the journal which published the paper that kicked off the anti-vax movement: https://en.wikipedia.org/wiki/Lancet_MMR_autism_fraud https://en.wikipedia.org/wiki/Lancet_MMR_autism_fraud
- andrepd 6y ago
  This is what GP means by "Wakefield".
- gamblor956 6y ago
  That is the Wakefield incident he was referring to.
yaj54 6y ago
TIL about the Wakefield incident. TY.
OJFord 6y ago
It also published [0] which seemed to be the ultimate source for the 'ibuprofen kills COVID-19 patients' scare, every article I found on ibuprofen+coronavirus led back there, which matter-of-factly states: > ACE2 can also be increased by thiazolidinediones and ibuprofen. The closest thing I could find [2] to a source for that was [1]: > NSAIDs [Non-Steroidal Anti-inflammatory Drugs, which includes ibuprofen] might affect how Covid-19 binds to human cells, according to Dr. Yogen Kanthi, assistant professor of cardiology at the University of Michigan, who studies inflammation. > “There is data from basic science studies that have shown that Covid-19 itself binds to a protein at the surface of cells called ACE2,” he said. “There is a hypothetical risk that giving NSAIDs like ibuprofen could increase levels of ACE2 shown in animal models, but not in patients.” [0] - https://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600(20)30116-8.pdf https://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600... [1] - https://kvia.com/health/2020/03/17/france-says-ibuprofen-may-aggravate-coronavirus-experts-say-more-evidence-is-needed/ https://kvia.com/health/2020/03/17/france-says-ibuprofen-may... [2] - https://news.ycombinator.com/item?id=22611363 https://news.ycombinator.com/item?id=22611363

salmon30salmon 6y ago

Edit: As OP mentioned, this is the "wakefield incident" Don't forget, The Lancet is also the journal which published the paper that kicked off the anti-vax movement: https://en.wikipedia.org/wiki/Lancet_MMR_autism_fraud https://en.wikipedia.org/wiki/Lancet_MMR_autism_fraud

andrepd 6y ago
This is what GP means by "Wakefield".
gamblor956 6y ago
That is the Wakefield incident he was referring to.

yaj54 6y ago

TIL about the Wakefield incident. TY.

OJFord 6y ago

It also published [0] which seemed to be the ultimate source for the 'ibuprofen kills COVID-19 patients' scare, every article I found on ibuprofen+coronavirus led back there, which matter-of-factly states: > ACE2 can also be increased by thiazolidinediones and ibuprofen. The closest thing I could find [2] to a source for that was [1]: > NSAIDs [Non-Steroidal Anti-inflammatory Drugs, which includes ibuprofen] might affect how Covid-19 binds to human cells, according to Dr. Yogen Kanthi, assistant professor of cardiology at the University of Michigan, who studies inflammation. > “There is data from basic science studies that have shown that Covid-19 itself binds to a protein at the surface of cells called ACE2,” he said. “There is a hypothetical risk that giving NSAIDs like ibuprofen could increase levels of ACE2 shown in animal models, but not in patients.” [0] - https://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600(20)30116-8.pdf https://www.thelancet.com/pdfs/journals/lanres/PIIS2213-2600... [1] - https://kvia.com/health/2020/03/17/france-says-ibuprofen-may-aggravate-coronavirus-experts-say-more-evidence-is-needed/ https://kvia.com/health/2020/03/17/france-says-ibuprofen-may... [2] - https://news.ycombinator.com/item?id=22611363 https://news.ycombinator.com/item?id=22611363