No. The adipocytes, aka the fat cells that can store energy, are in limited supply. Some people have a more flexible adipose tissue then others. Some people ca

No. The adipocytes, aka the fat cells that can store energy, are in limited supply. Some people have a more flexible adipose tissue then others. Some people can store very little or no subcutaneous fat at all, all of the accumulated fat is stored as visceral fat (around their organs), which is limited, so they look skinny on the outside, fit even, but suffer from T2D nonetheless. Here are some references: https://portlandpress.com/clinsci/article/128/7/405/71158/Normal-weight-individuals-who-develop-Type-2 https://portlandpress.com/clinsci/article/128/7/405/71158/No... https://diabetes.diabetesjournals.org/content/63/12/4369 https://diabetes.diabetesjournals.org/content/63/12/4369 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774584/ https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774584/ Basically insulin resistance, high blood glucose and the ensuing loss of beta cell function in the pancreas happen as a result of adipocytes starting to reject excess energy, which then remains in the bloodstream and is being pissed away. Insulin resistance in many circles is understood as the cause of T2D, however insulin resistance is actually a defensive mechanism, in response to energy poisoning. https://www.pnas.org/content/106/42/17787 https://www.pnas.org/content/106/42/17787 And the source of that excess doesn't matter, all macro nutrients can cause insulin resistance, even if via different pathways: https://pubmed.ncbi.nlm.nih.gov/3421919/ https://pubmed.ncbi.nlm.nih.gov/3421919/ https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2362.32.s3.3.x https://onlinelibrary.wiley.com/doi/abs/10.1046/j.1365-2362.... https://pubmed.ncbi.nlm.nih.gov/11872656/ https://pubmed.ncbi.nlm.nih.gov/11872656/