3 ms·

"[triglyceride and glucose] index was closely associated with the severity and morbidity in COVID-19" So perhaps part of the reason why COVID-19 morbidity is l

"[triglyceride and glucose] index was closely associated with the severity and morbidity in COVID-19" So perhaps part of the reason why COVID-19 morbidity is lower in Japan/Korea/Taiwan compared to the U.S. is due to lower prevalence of metabolic syndrome. I wonder if that's also true for Europe.

arkades 6y ago
> It suggests a protective effect of a keto/paleo diet. No, if it can be taken at face value, it suggests a protective effect of a healthy lifestyle.
- floatingatoll 6y ago
  If taken at face value, it suggests a protective effect of low insulin resistance as measured by the TyG marker. Everything else is interpretations and chains of logical reasoning. Neither of you are particularly wrong necessarily, but a third option is that someone could be sedentary and eating carbs every day and have low TyG. It's common to state that "activity XYZ will provide action-at-a-distance medical benefit ABC" because stating accurately what's going on takes more words that sound less certain: "Paleo and keto diets may weaken Covid-19 by lowering insulin resistance" "A healthy lifestyle may weaken Covid-19 by lowering insulin resistance" But it's really worth saying it like this, even though few do. (And yes, these aren't 'maybe' enough, but they're an improvement.)
  - arkades 6y ago
    You replaced the word "suggests" with "may". You're seeing a distinction between these two words that I apparently do not, since I take them both to indicate "this is a possibility, though not the only one, and a far from proven certainty." I would add that, even there, my statement was predicated on making an inference about dietary habits - something I cast doubt on with the opening, "if taken at face value." Something I further opined on in my other post, where I pointed out that the paper may be reversing causality. I feel like you're criticizing a strong inference having been made, that I think pretty clearly wasn't.
doctoring 6y ago
It suggests a protective effect of being healthier in general. Japan/Korea/Taiwan/elsewhere have lower rates of metabolic syndrome than the U.S. not because they're on a keto/paleo diet... (Nothing against a keto/paleo diet, just it's not really necessary.)

arkades 6y ago

> It suggests a protective effect of a keto/paleo diet. No, if it can be taken at face value, it suggests a protective effect of a healthy lifestyle.

floatingatoll 6y ago
If taken at face value, it suggests a protective effect of low insulin resistance as measured by the TyG marker. Everything else is interpretations and chains of logical reasoning. Neither of you are particularly wrong necessarily, but a third option is that someone could be sedentary and eating carbs every day and have low TyG. It's common to state that "activity XYZ will provide action-at-a-distance medical benefit ABC" because stating accurately what's going on takes more words that sound less certain: "Paleo and keto diets may weaken Covid-19 by lowering insulin resistance" "A healthy lifestyle may weaken Covid-19 by lowering insulin resistance" But it's really worth saying it like this, even though few do. (And yes, these aren't 'maybe' enough, but they're an improvement.)
- arkades 6y ago
  You replaced the word "suggests" with "may". You're seeing a distinction between these two words that I apparently do not, since I take them both to indicate "this is a possibility, though not the only one, and a far from proven certainty." I would add that, even there, my statement was predicated on making an inference about dietary habits - something I cast doubt on with the opening, "if taken at face value." Something I further opined on in my other post, where I pointed out that the paper may be reversing causality. I feel like you're criticizing a strong inference having been made, that I think pretty clearly wasn't.

doctoring 6y ago

It suggests a protective effect of being healthier in general. Japan/Korea/Taiwan/elsewhere have lower rates of metabolic syndrome than the U.S. not because they're on a keto/paleo diet... (Nothing against a keto/paleo diet, just it's not really necessary.)