3 ms·
The thing is, we already are doing way riskier experiments to deal with COVID. We sent the Moderna vaccine into human trials with barely any mouse data at all.
by vikramkr 6y ago
The thing is, we already are doing way riskier experiments to deal with COVID. We sent the Moderna vaccine into human trials with barely any mouse data at all. What Hanson is proposing is giving his pet approach, inoculation with live virus, special treatment. The reason we're not pouring time and money into validating inoculation is because we have literally dozens of vaccine platforms, some with decades of evidence backing them up, that promise far higher theoretical safety and efficacy than inoculation's theoretical safety and efficacy. We'd rather pour our focus into approaches like moderna's vaccine, which could be highly scalable, and J&Js vaccine and AstraZeneca's vaccine because those platforms are known to work in other diseases. We've got companies like Codagenix using the tools of molecular biology to create attenuated forms of the virus without tradition time consuming development techniques. When we already have these candidates developed and have them barreling forward, why would anyone want to spend time and effort developing and testing a worse approach? The risk/reward doesn't make sense.
- cameldrv 6y agoYes, but it's uncertain when those vaccines will be available or whether they will work. Even as a backup plan, it makes sense to me to evaluate variolation. With millions of lives worldwide and the entire global economy on the line, you do not want to put all your eggs into even ten baskets. As for the time and effort, I'm assuming that the existing vaccine developments are adequately staffed. There are many other medical researchers that are working on other things that could work on this.