Oxidative stress, why? I’m really confused at why we don’t think of the mechanics of this disease in terms of the cell and tissue types that express ACE2 recept

Oxidative stress, why? I’m really confused at why we don’t think of the mechanics of this disease in terms of the cell and tissue types that express ACE2 receptors. ACE and ACE2 receptors regulate fluid pressure. ACE increases pressure by constricting tissue and ACE2 decreases pressure by dilating tissue. ACE2 receptors are found in the lungs, blood vessels, heart, kidneys, and gastrointestinal system. This makes sense and matches the pathogenesis of SARS-CoV. SARS-CoV-2 also infects the epithelial cells of the upper respiratory tract, like the cold-like HCoV-NL63. All the symptoms seem to match the spread of the virus to new tissue types. The timing matches too, with each new tissue type having an independent incubation period. Am I missing something? Children only seem to be susceptible to gastrointestinal infection which looks like Kawasaki’s disease when it spreads to adjoining blood vessels.