While a laptop is fine with regards to performance (especially when expensive computations are done on a remote server), it's not with regards to comfort and up

While a laptop is fine with regards to performance (especially when expensive computations are done on a remote server), it's not with regards to comfort and upgradability. I'd rather have a small computer with quiet cooling, proper keyboard, mouse and screens than whichever laptop you can get even with an extensive budget. Even when it comes to desk clutter, I'd rather have only a keyboard and a mouse than a whole laptop. Writing this from a laptop, btw.