Well, if the main issue is Time Zone and you're American, American companies can simply hire across America. That's a gigantic talent pool that wasn't available

Well, if the main issue is Time Zone and you're American, American companies can simply hire across America. That's a gigantic talent pool that wasn't available before. But I think at first it will just move from SF / New York to cheaper U.S states. After a few years of gaining experience in managing remote work, we'll probably see more hiring across the world. Note that only rather big scale ups can afford to do that, hiring from a different country is an accounting headache. So young startup workers aren' likely to be hit.