Numerous interrupts may have an impact on latency, but for backpressure, buffering in the network layer or the filesystem/block layer can hide the limitations o

Numerous interrupts may have an impact on latency, but for backpressure, buffering in the network layer or the filesystem/block layer can hide the limitations of the system from your application, and when you hit those limits, the hit is harder and can cause oscillations throughout a network or distributed system. Now, of course, applications themselves can fail at this too. Look at Postgres, maybe, where typically people rely on [AUTO]VACUUM, but if your application runs continuously, then there is no right time to run it.